Mechanism of BceAB-type transporter: Resistance by lipid II flipping
J. Zaschke-Kriesche, S. Unsleber, I. Voitsekhovskaia, A. Kulik, L. Behrmann, N. Overbeck, K. Stuehler, E. Stegmann, S. Smits
The paper identifies SaNsrFP as a BceAB-type transporter that confers resistance to antimicrobial peptides by flipping lipid II back into the cytosol, reducing its availability on the cell surface.
bioRxiv · Mar 5, 2020 · PreprintMicrobiology