Author

N. Riggi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Avgustinova· 1 shared A. B. Haynes· 1 shared A. Muhlethaler-Mottet· 1 shared A. Petit· 1 shared A. R. Richman· 1 shared A. Regev· 1 shared A. Volorio· 1 shared B. Haas· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

A. Avgustinova

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3 papers

Recent·Most cited

KDM6 demethylases mediate EWSR1-FLI1-driven oncogenic transformation in Ewing Sarcoma

E. Figuerola-Bou, C. Rios-Astorch, E. Blanco, M. Sanchez-Jimenez, P. Taboas, G. Fernandez, S. Gomez, O. Munoz, P. Castellano-Escuder, S. Perez-Jaume, E. Prada, S. Mateo-Lozano, N. Riggi, A. Avgustinova, C. Lavarino, , J. Mora

This study identifies KDM6A and KDM6B as EWSR1-FLI1 cofactors in Ewing Sarcoma, showing distinct roles in enhancer activation and tumor growth.

bioRxiv · Jan 24, 2023Cancer Biology

TWIST1 expression is associated with high-risk Neuroblastoma and promotes Primary and Metastatic Tumor Growth

M.-V. Sepporta, V. Praz, K. Balmas Bourloud, J.-M. Joseph, N. Jauquier, N. Riggi, K. Nardou-Auderset, A. Petit, J.-Y. Scoazec, H. Sartelet, R. Renella, A. Muhlethaler-Mottet

This study shows TWIST1 promotes neuroblastoma growth and metastasis, and its suppression reduces tumor aggressiveness in mice.

bioRxiv · Mar 22, 2021Cancer Biology

Opposing immune and genetic forces shape oncogenic programs in synovial sarcoma

L. Jerby, C. Neftel, M. E. Shore, M. J. McBride, B. Haas, B. Izar, H. R. Weissman, A. Volorio, G. Boulay, L. Cironi, A. R. Richman, L. C. Broye, J. M. Gurski, C. C. Luo, R. Mylvaganam, , A. Regev

The paper profiles synovial sarcoma tumors to show that the SS18-SSX fusion drives oncogenic programs, which are repressed by immune cells and can be targeted with HDAC and CDK4/6 inhibitors.

bioRxiv · Aug 4, 2019 · PreprintCancer Biology