A novel inhibitor of complement C5 provides structural insights into activation
M. Reichhardt, S. Johnson, T. Tang, T. Morgan, N. Tebeka, N. Popitsch, J. Deme, M. jore, S. M. Lea
The paper identifies a novel inhibitor from tick saliva, determines its structure bound to complement C5, and reveals a new mechanism of C5 inhibition.
bioRxiv · Jun 10, 2019Immunology