ImmunologybioRxivPreprint
Endosomal LRBA regulates the endo-lysosomal pathway
Viktória Szentgyörgyi, Leon Maximilian Lueck, Daan Overwijn…·Shahrzad Bakhtiar
This study identifies LRBA's role in regulating the endosomal-lysosomal pathway by controlling Rab4+ endosome traffic, leading to enlarged endolysosomes in LRBA-deficient patients.
DOI 10.1101/2024.02.07.579084