Resource Profile and User Guide of the Polygenic Index Repository
Joël Becker, Casper A.P. Burik, Grant Goldman, Nancy Wang, Hariharan Jayashankar, Michael Bennett, Daniel W. Belsky, Richard Karlsson Linnér, Rafael Ahlskog, Aaron Kleinman, David A. Hinds, Michelle Agee, Babak Alipanahi, Adam Auton, Robert K. Bell, , Aysu Okbay
The paper constructs polygenic indexes for 47 phenotypes across 11 datasets and provides a tool to correct errors-in-variables bias when using PGIs as proxies for the additive SNP factor.
Nature Human Behaviour · Jun 17, 2021Peer-reviewedGenomics