Cell BiologybioRxivPreprint
The Specificity of IQGAP1 Toward the PI3K-Akt Pathway is Dependent on the IQ3 motif
Mo Chen, Tianmu Wen, Suyong Choi…·Richard A. Anderson
This study identifies the IQ3 motif in IQGAP1 as critical for specific PI3K-Akt pathway scaffolding, without affecting Ras-ERK pathway functions or cell migration.
DOI 10.1101/250936