Developmental BiologybioRxiv
Single-Cell Sequencing of Primate Preimplantation Embryos Reveals Chromosome Elimination Via Cellular Fragmentation and Blastomere Exclusion
Brittany L. Daughtry, Jimi L. Rosenkrantz, Nathan H. Lazar…·Shawn L. Chavez
The paper uses single-cell DNA sequencing in non-human primates to show that chromosomal errors in embryos are encapsulated into micronuclei, fragmented, or excluded to prevent aneuploidy.