NeuroscienceCell ReportsPeer-reviewed
Synaptic plasticity in human thalamocortical assembloids
Mary H. Patton, Kristen T. Thomas, Ildar T. Bayazitov…·Stanislav S. Zakharenko
This paper demonstrates that thalamocortical assembloids formed from human organoids exhibit functional glutamatergic synapses with short-term plasticity and distinct long-term potentiation and depression mechanisms compared to rodents.