GeneticsbioRxivPreprint
Causal considerations can determine the utility of machine learning assisted GWAS
Sumit Mukherjee, Zachary Ryan McCaw, David Amar…·Colm T. O’Dushlaine
This study shows that machine learning-derived phenotypes for GWAS can lead to false discoveries depending on their causal relationship with the target phenotype and environment.
DOI 10.1101/2024.12.16.628604