High-content screening identifies FDA-approved activators of mitophagy
Carlo Viscomi, Giacomo Giacchin, Valeria Balmaceda…·Cristiane Benincá
The paper screens FDA-approved compounds to find mitophagy activators, identifying Meptazinol and Ponatinib as top candidates that increase mitolysosomes but do not rescue bioenergetic defects in mitochondrial diseases.