Author

Ning Sun

Nanjing General Hospital of Nanjing Military Command

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Genetics· 3 Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

Aimin PaniD· 1 shared Andrew Liem· 1 shared Andrew XiaoiD· 1 shared Anni Li· 1 shared Baolin Yang· 1 shared Bin Cui· 1 shared Bomiao HuiD· 1 shared Bryan R. GormaniD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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1 shared paperBioinformatics

Aimin PanORCID

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Author profile →

5 papers

Recent·Most cited

Benchmarking Perturbation Tools for the Noncoding Genome

Han Zhang, Shijie Luo, Xiaofeng Wang, Liquan Lin, Ruipu Liang, Chunge Zhong, Yunhan Zhang, Wenchang Zhao, Zhisong Chen, Xiaoya Liu, Feng Chen, Ning Sun, Jialiang Huang, Fei Teng

This study benchmarks five loss-of-function perturbation tools for studying noncoding genome function, finding dual-SpCas9 is most effective for targeting CREs and recommending RNA interference for noncoding RNA genes.

bioRxiv · Oct 21, 2025 · PreprintGenetics

Epigenetic priming promotes acquisition of tyrosine kinase inhibitor resistance and oncogene amplification in human lung cancer

Rebecca M. Starble, Eric G. Sun, Rana Gbyli, Jonathan S. D. Radda, Jiuwei Lu, Tyler B Jensen, Ning Sun, Nelli Khudaverdyan, Bomiao Hu, Mary Ann Melnick, Shuai Zhao, Nitin Roper, Gang Greg Wang, Jikui Song, Katerina A. Politi, , Andrew Xiao

The paper identifies METTL7A as a factor that promotes TKI resistance and oncogene amplification in lung cancer by remodeling chromatin structure before copy number gains.

bioRxiv · Jan 26, 2025 · PreprintGenetics

InstructPLM: Aligning Protein Language Models to Follow Protein Structure Instructions

Jiezhong Qiu, Junde Xu, Jie Hu, Hanqun Cao, Liya Hou, Zi-Jun Gao, Xinyi Zhou, Anni Li, Xiujuan Li, Bin Cui, Fei Yang, Shuang Peng, Ning Sun, Fangyu Wang, Aimin Pan, , Guangyong Chen

InstructPLM aligns a protein language model with structure instructions to generate diverse proteins, improving performance over existing models in sequence recovery and activity.

bioRxiv · Apr 17, 2024 · PreprintBioinformatics

The nervous system is the major target for Gold nanoparticle: Evidence from RNA sequencing data of C. elegans

Jihao Mo, Ning Sun, Baolin Yang, Shaoxia Li, Lei Wang

The paper shows that gold nanoparticles primarily affect the nervous system in C. elegans, causing oxidative stress and disrupting neuron communication.

bioRxiv · Jan 13, 2020 · PreprintNeuroscience

Measuring genetic variation in the multi-ethnic Million Veteran Program (MVP)

Haley Hunter-Zinck, Yunling Shi, Man Li, Bryan R. Gorman, Sun‐Gou Ji, Ning Sun, Teresa A. Webster, Andrew Liem, Paul Hsieh, Poornima Devineni, Purushotham Karnam, Lakshmi Radhakrishnan, Jeanette P. Schmidt, Themistocles L. Assimes, Jie Huang, , on behalf of the VA Million Veteran Program

The paper describes the design and performance of the MVP 1.0 custom Axiom array for genotyping a diverse cohort, achieving high-quality genetic data with substantial ancestral diversity.

bioRxiv · Jan 6, 2020 · PreprintGenetics