Tyler B Jensen

The paper maps 3D genome structures in cancer tissues to identify structural changes and potential biomarkers across cancer progression stages.

The paper introduces Perturb-tracing, a high-content screening platform to identify regulators of 3D chromatin organization, discovering new factors that influence chromatin folding and nuclear architecture.

The paper identifies METTL7A as a factor that promotes TKI resistance and oncogene amplification in lung cancer by remodeling chromatin structure before copy number gains.

This study investigates Neuregulin-1's role in axolotl lung regeneration via ErbB receptors, showing its necessity for proliferation and regeneration.