Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations
S. Nishijima, E. Stankevic, O. Aasmets, T. S. Schmidt, N. Nagata, M. I. Keller, P. Ferretti, H. Juel, A. Fullam, C. Schudoma, S. M. Robbani, J. K. Hansen, L. A. Holm, M. Israelsen, R. Schierwagen, , P. Bork
This study shows that fecal microbial load, not disease, is the main driver of gut microbiome changes and identifies it as a major confounder in microbiome studies.
bioRxiv · Mar 18, 2024Microbiology