T. S. Schmidt

Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations

This study shows that fecal microbial load, not disease, is the main driver of gut microbiome changes and identifies it as a major confounder in microbiome studies.

Development of non-alcoholic steatohepatitis is associated with gut microbiota but not oxysterol synthesis

This study investigates the role of gut microbiota and the EBI2-oxysterol axis in NASH development using a mouse model, finding microbiota differences but no link between the EBI2 axis and microbiota.

C. difficile may be overdiagnosed in adults and is a prevalent commensal in infants

This study finds that C. difficile is often overdiagnosed in adults and is a common commensal in infants, with distinct microbial associations across age groups.

Alterations of oral microbiota and impact on the gut microbiome in type 1 diabetes mellitus revealed by multi-omic analysis

This study identifies oral microbiota changes in T1DM linked to gut microbiome alterations through multi-omic analysis of saliva and stool samples.

Functional and evolutionary significance of unknown genes from uncultivated taxa

The paper identifies and analyzes novel protein families from uncultivated microbes, revealing their evolutionary significance and potential ecological roles.

Drivers and Determinants of Strain Dynamics Following Faecal Microbiota Transplantation

This study identifies recipient and donor microbiome factors that determine strain dynamics after FMT, independent of clinical outcomes.

Extensive Transmission of Microbes along the Gastrointestinal Tract

The paper shows oral microbes commonly colonize the large intestine in healthy individuals and more so in disease states like colorectal cancer and rheumatoid arthritis.