Author

O. Acar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Evolutionary Biology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A.-R. Carvunis· 2 shared N. Vakirlis· 2 shared A. Armutlu· 1 shared A. Chiang· 1 shared A. F. O'Donnell· 1 shared A. F. ODonnell· 1 shared A. McLysaght· 1 shared A. Senturk· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersEvolutionary Biology

A.-R. Carvunis

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ancestral Sequence Reconstruction as a tool to detect and study de novo gene emergence

N. Vakirlis, O. Acar, V. K. Cherupally, A.-R. Carvunis

This study evaluates Ancestral Sequence Reconstruction (ASR) as a tool to detect de novo genes by analyzing ~2,600 yeast genes and identifying 33 de novo emerged genes.

bioRxiv · Jan 2, 2024Evolutionary Biology

α-Arrestins maintain phospholipid balance and Atg18 distribution to permit efficient autophagy

R. W. Bowman, S. Davis, E. M. Jordahl, K. Chera, N. Ozbaki-Yagan, J. Franks, S. Hawbaker, A. Chiang, O. Acar, D. Beer-Stoltz, A. F. ODonnell

This study identifies a role for α-arrestins in maintaining phospholipid balance and Atg18 distribution to support efficient autophagy.

bioRxiv · Aug 3, 2022 · PreprintCell Biology

Quantitative proteomics identifies secreted diagnostic biomarkers as well as tumor-dependent prognostic targets for clear cell Renal Cell Carcinoma

A. Senturk, A. T. Sahin, A. Armutlu, M. C. Kiremit, O. Acar, S. Erdem, S. Bagbudar, T. Esen, N. Tuncbag, N. Ozlu

The paper uses quantitative proteomics to identify secreted biomarkers and prognostic targets in ccRCC, finding SPARC as a promising diagnostic marker and proposing a biomarker panel for prognosis.

bioRxiv · Feb 8, 2021Cancer Biology

De novo emergence of adaptive membrane proteins from thymine-rich intergenic sequences

N. Vakirlis, O. Acar, B. Hsu, N. Castilho Coelho, S. B. Van Oss, A. Wacholder, K. Medetgul-Ernar, J. Ianotta, A. McLysaght, C. J. Camacho, A. F. O'Donnell, T. Ideker, A.-R. Carvunis

This study shows that de novo emerging coding sequences in yeast often encode beneficial transmembrane proteins, suggesting that intergenic regions may contain pre-existing blueprints for such functions.

bioRxiv · Apr 29, 2019Evolutionary Biology