Author

A. T. Sahin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1

Frequent Co-Authors

U. Zachariae· 2 shared A. Armutlu· 1 shared A. Senturk· 1 shared C. M. Ives· 1 shared M. C. Kiremit· 1 shared N. J. Thomson· 1 shared N. Ozlu· 1 shared N. Tuncbag· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiophysics

U. Zachariae

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiophysicsbioRxivPreprintNov 1, 2023

Characterisation of ligand gating, ion conduction and the ion selectivity mechanism in the endo-lysosomal ion channel hTPC2

A. T. Sahin, U. Zachariae

This study uses simulations to investigate how the lipid PI(3,5)P2 affects ion selectivity and activation of hTPC2, revealing structural changes and ion permeation mechanisms.

DOI 10.1101/2023.11.01.565142

humandeep learning

𝕏 PostBluesky

BiophysicsbioRxivJan 11, 2023

A hydrophobic funnel governs monovalent cation selectivity in the ion channel TRPM5

C. M. Ives, A. T. Sahin, N. J. Thomson, U. Zachariae

This study identifies a hydrophobic funnel in TRPM5 that enables monovalent cation selectivity by blocking divalent cations through a unique mechanism.

DOI 10.1016/j.bpj.2024.07.035

electrophysiologybiophysical modeling

𝕏 PostBluesky

Cancer BiologybioRxivFeb 8, 2021

Quantitative proteomics identifies secreted diagnostic biomarkers as well as tumor-dependent prognostic targets for clear cell Renal Cell Carcinoma

A. Senturk, A. T. Sahin, A. Armutlu…·N. Ozlu

The paper uses quantitative proteomics to identify secreted biomarkers and prognostic targets in ccRCC, finding SPARC as a promising diagnostic marker and proposing a biomarker panel for prognosis.

DOI 10.1158/1541-7786.mcr-21-0004

humanproteomics

𝕏 PostBluesky