Human Induced Pluripotent Stem Cell based Hepatic-Modeling of Lipid metabolism associated TM6SF2 E167K variant
L. A. P. Faccioli, Y. Sun, T. Motomura, Z. Liu, T. Kurihara, Z. Hu, Z. Cetin, J. Franks, D. Stolz, A. Ostrowska, R. M. Florentino, I. J. Fox, A. Soto-Gutierrez
This study creates a human iPSC-derived hepatocyte model with the TM6SF2 E167K mutation to study its effects on lipid metabolism and MASLD.
bioRxiv · Dec 18, 2023Cell Biology