Author

O. Drechsel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:Hi-C· 1 Organism:human· 1

Frequent Co-Authors

A. Mizi· 1 shared A. Papantonis· 1 shared B. A. M. Bouwman· 1 shared C. F. Nielsen· 1 shared D. F. Hudson· 1 shared E. G. Gusmao· 1 shared E.-M. Wagner· 1 shared G. Petrosino· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. Mizi

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1 paper

Recent·Most cited

Spatial chromosome folding and active transcription drive DNA fragility and formation of oncogenic MLL translocations

H. J. Gothe, B. A. M. Bouwman, E. G. Gusmao, R. Piccinno, S. Sayols, O. Drechsel, G. Petrosino, V. Minneker, N. Josipovic, A. Mizi, C. F. Nielsen, E.-M. Wagner, S. Takeda, H. Sasanuma, D. F. Hudson, , V. Roukos

The paper shows that transcription and spatial chromosome folding increase DNA fragility, leading to oncogenic translocations in leukemia.

bioRxiv · Dec 3, 2018Cell Biology