Cilium induction triggers differentiation of glioma stem cells
G. Goranci-Buzhala, A. Mariappan, L. Ricci-Vitiani, N. Josipovic, S. Pacion, M. Gottardo, J. Ptok, G. C. Callaini, K. Rajalingam, B. Dynlacht, K. Hadian, A. Papantonis, R. Pallini, J. Gopalakrishnan
This study shows that inducing ciliogenesis in glioma stem cells (GSCs) promotes their differentiation and prevents brain infiltration, suggesting cilium induction as a therapeutic strategy for glioblastoma.
bioRxiv · Dec 23, 2020Cell Biology