Author

E. G. Gusmao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:DNA methylation· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

A. Papantonis· 3 shared N. Crosetto· 2 shared N. Josipovic· 2 shared A. Angelopoulou· 1 shared A. Hoischen· 1 shared A. Maya-Mendoza· 1 shared A. Mizi· 1 shared A. Polyzos· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCell Biology

A. Papantonis

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Author profile →

3 papers

Recent·Most cited

Cell BiologybioRxivDec 20, 2020

Genomic instability is an early event driving chromatin reorganization and escape from oncogene-induced senescence

C. Zampetidis, P. Galanos, A. Angelopoulou…·V. G. Gorgoulis

The paper identifies an early chromosomal inversion that enables escape from oncogene-induced senescence by activating BHLHE40 and promoting malignant transformation.

DOI 10.1016/j.molcel.2021.10.017

humanwhole-genome sequencing

𝕏 PostBluesky

Cell BiologybioRxivJan 27, 2020

Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology

Y. Kargapolova, R. Rehimi, H. Kayserli…·A. Papantonis

The paper identifies a CHD6 mutation causing Hallermann-Streiff syndrome and shows it disrupts autophagy and DNA damage response through chromatin remodeling.

DOI 10.1038/s41467-021-23327-1

humanDNA methylation

𝕏 PostBluesky

Cell BiologybioRxivDec 3, 2018

Spatial chromosome folding and active transcription drive DNA fragility and formation of oncogenic MLL translocations

H. J. Gothe, B. A. M. Bouwman, E. G. Gusmao…·V. Roukos

The paper shows that transcription and spatial chromosome folding increase DNA fragility, leading to oncogenic translocations in leukemia.

DOI 10.1016/j.molcel.2019.05.015

humanDNA methylation

𝕏 PostBluesky