Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 Spike protein
H. Caohuy, O. Eidelman, T. Chen, Q. Yang, B. S. Pollard, N. I. Walton, H. B. Pollard
This paper shows that SARS-CoV-2 Spike protein inhibits CFTR signaling in airway epithelia, leading to inflammation similar to cystic fibrosis.
bioRxiv · Jan 18, 2022Microbiology