MicrobiologybioRxiv
Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 Spike protein
H. Caohuy, O. Eidelman, T. Chen…·H. B. Pollard
This paper shows that SARS-CoV-2 Spike protein inhibits CFTR signaling in airway epithelia, leading to inflammation similar to cystic fibrosis.
DOI 10.1038/s41598-024-66473-4