O. Espeli

Assessing in vivo the impact of gene context on transcription through DNA supercoiling

The paper assesses how gene context affects transcription in vivo by measuring gene expression in E. coli with varying distances to topological barriers and promoters.

Prophage taming by the adherent-invasive Escherichia coli LF82 upon macrophage infection

This paper studies prophage activity in the adherent-invasive E. coli LF82 strain, showing it tames its most active prophage during macrophage infection to enhance survival.

Transcriptional units form the elementary constraining building blocks of the bacterial chromosome

The paper shows that transcriptional units form discrete 3D domains that constrain bacterial chromosome organization at a fine scale.

The Crohn's disease-related AIEC strain LF82 assembles a biofilm-like matrix to protect intracellular microcolonies from phagolysosomal attack

This study shows that the AIEC strain LF82 forms a biofilm-like matrix to protect intracellular bacterial communities from phagolysosomal attack in macrophages.

The Crohn s disease-associated Escherichia coli strain LF82 rely on SOS and stringent responses to survive, multiply and tolerate antibiotics within macrophages.

This study investigates how AIEC LF82 survives and multiplies in macrophages, revealing phenotypic switches and antibiotic tolerance mechanisms.