N. Barnich

Biochemical characterization of the Escherichia coli surfaceome: A focus on type I fimbriae and flagella.

This study characterizes the glycosylation of surface proteins in E. coli, focusing on type I fimbriae and flagella, revealing chemically resistant glycans and unexpected glycan structures.

The Colibactin-Producing Escherichia coli alters the tumor microenvironment to immunosuppressive lipid overload facilitating colorectal cancer progression and chemoresistance.

This study shows that Colibactin-producing Escherichia coli creates an immunosuppressive lipid-rich tumor microenvironment that promotes colorectal cancer progression and chemoresistance.

Mucolytic bacteria license pathobionts to acquire host-derived nutrients during dietary nutrient restriction

The paper shows that mucolytic bacteria enable pathobionts to acquire host-derived nutrients during dietary restriction, allowing them to thrive in the gut.

The Crohn's disease-related AIEC strain LF82 assembles a biofilm-like matrix to protect intracellular microcolonies from phagolysosomal attack

This study shows that the AIEC strain LF82 forms a biofilm-like matrix to protect intracellular bacterial communities from phagolysosomal attack in macrophages.

Innate immune recognition of a bacterial MAMP leads to conditional activation of pro- or anti-inflammatory responses

This study shows that flagellin, a bacterial MAMP, can trigger either pro- or anti-inflammatory responses depending on the tissue's physiological state and context.

The Crohn s disease-associated Escherichia coli strain LF82 rely on SOS and stringent responses to survive, multiply and tolerate antibiotics within macrophages.

This study investigates how AIEC LF82 survives and multiplies in macrophages, revealing phenotypic switches and antibiotic tolerance mechanisms.