Author

C. Sponholz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Ramoji· 1 shared B. Goehrig· 1 shared B. Loeffler· 1 shared C. Beemelmanns· 1 shared D. Thomas-Rüddel· 1 shared F. Bloos· 1 shared H. Guo· 1 shared I. Leonhardt· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Ramoji

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Gram-positive bacteria secrete RNA aptamers to activate human STING for IL-1β release.

S. N. Duduskar, M. Ghait, M. Westermann, H. Guo, A. Ramoji, C. Sponholz, B. Goehrig, T. Bruns, U. Neugebauer, J. Popp, L. P. N. Tuchscherr, B. Loeffler, N. Ueberschaar, C. Beemelmanns, M. Singer, , S. D. Deshmukh

This study identifies RNA aptamers secreted by Gram-positive bacteria that activate the STING pathway to induce IL-1β release in human macrophages.

bioRxiv · Jul 21, 2021 · PreprintImmunology

Ex vivo Immune Profiling in Patient Blood enables Quantification of innate immune Effector Functions

T. Lehnert, I. Leonhardt, S. Timme, D. Thomas-Rüddel, F. Bloos, C. Sponholz, O. Kurzai, M. T. Figge, K. Hünniger

The paper quantifies innate immune effector functions in patient blood after ex vivo infection, revealing altered immune responses post-cardiac surgery.

bioRxiv · Oct 1, 2020Immunology