Author

O. Mitja

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:long-read sequencing· 1 Research Focus:phylogenetics / evolution· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Haynes· 2 shared E. Romeis· 2 shared L. Giacani· 2 shared M. Eguiluz· 2 shared A. C. Sena· 1 shared A. L. Greninger· 1 shared A. Rompalo· 1 shared B. Chung· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

A. Haynes

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

High-throughput nanopore sequencing of Treponema pallidum tandem repeat genes arp and tp0470 reveals clade-specific patterns and recapitulates global whole genome phylogeny

N. A. P. Lieberman, T. D. Armstrong, B. Chung, D. Pfalmer, C. M. Hennelly, A. Haynes, E. Romeis, Q.-Q. Wang, R.-L. Zhang, C.-X. Kou, G. Ciccarese, I. Dal Conte, M. Cusini, F. Drago, S.-i. Nakayama, , A. L. Greninger

The paper uses nanopore sequencing to analyze repeat regions in T. pallidum genes, revealing clade-specific patterns that align with whole genome phylogeny.

bioRxiv · Aug 2, 2022Microbiology

SARS-CoV-2 infection suppresses ACE2 function and antiviral immune response in the upper respiratory tract of infected patients

L. Gutierrez-Chamorro, E. Riveira-Munoz, C. Barrios, V. Palau, M. Massanella, E. Garcia-Vidal, R. Badia, S. Pedreno, J. Senserrich, E. Rodriguez, B. Clotet, C. Cabrera, O. Mitja, M. Crespo, J. Pascual, , E. Ballana

This study shows SARS-CoV-2 reduces ACE2 activity and antiviral gene expression in the upper respiratory tract, while initially increasing interferon-stimulated genes.

bioRxiv · Nov 18, 2020 · PreprintImmunology

Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum

A. Haynes, M. Fernandez, E. Romeis, O. Mitja, K. Konda, S. Vargas, M. Eguiluz, C. Caceres, J. Klausner, L. Giacani

This paper investigates the transcriptional regulation of the TprL gene in Treponema pallidum, showing that phase variation through homopolymeric G sequences affects its expression and immune response.

bioRxiv · Sep 28, 2020Microbiology