Author

B. Chung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Bioengineering· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. L. Greninger· 2 shared D. H. Barouch· 2 shared E. Romeis· 2 shared H. Andersen· 2 shared K. Lee· 2 shared K. McMahan· 2 shared L. Giacani· 2 shared M. G. Lewis· 2 shared

Activity by Year

2019-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

A. L. Greninger

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Reinstating targeted protein degradation with DCAF1 PROTACs in CRBN PROTAC resistant settings

M. Schroeder, M. Renatus, X. Liang, F. Meili, S. Ferrand, F. Gauter, X. Li, F. Sigoillot, S. Gleim, M.-T. Stachyra, J. Thomas, M. Schirle, T. Zoller, D. Begue, P. Lefeuvre, , C. R. Thoma

This study develops DCAF1-based PROTACs to overcome CRBN resistance in targeted protein degradation, demonstrating effective degradation of BTK in CRBN-resistant cells.

bioRxiv · Apr 9, 2023 · PreprintBiochemistry

Treponema pallidum subsp. pallidum with an Artificially Impaired TprK Antigenic Variation System is Attenuated in the Rabbit Model of Syphilis

E. Romeis, N. A. P. Lieberman, B. J. Molini, L. C. Tantalo, B. Chung, Q. Phung, C. Avendano, A. Vorobieva, A. L. Greninger, L. Giacani

This study creates a T. pallidum strain with impaired TprK antigenic variation and shows it is attenuated in a rabbit syphilis model.

bioRxiv · Jan 18, 2023 · PreprintMicrobiology

High-throughput nanopore sequencing of Treponema pallidum tandem repeat genes arp and tp0470 reveals clade-specific patterns and recapitulates global whole genome phylogeny

N. A. P. Lieberman, T. D. Armstrong, B. Chung, D. Pfalmer, C. M. Hennelly, A. Haynes, E. Romeis, Q.-Q. Wang, R.-L. Zhang, C.-X. Kou, G. Ciccarese, I. Dal Conte, M. Cusini, F. Drago, S.-i. Nakayama, , A. L. Greninger

The paper uses nanopore sequencing to analyze repeat regions in T. pallidum genes, revealing clade-specific patterns that align with whole genome phylogeny.

bioRxiv · Aug 2, 2022Microbiology

Vaccine Protection Against the SARS-CoV-2 Omicron Variant in Macaques

A. Chandrashekar, J. Yu, K. McMahan, C. Jacob-Dolan, J. Liu, X. He, D. Hope, T. Anioke, J. Barrett, B. Chung, N. Hachmann, M. Lifton, J. Miller, O. Powers, M. Sciacca, , D. H. Barouch

This study evaluates vaccine efficacy against SARS-CoV-2 Omicron in macaques, finding that both humoral and cellular immune responses are necessary for virologic control.

bioRxiv · Feb 6, 2022Microbiology

High-performance Flexible Microelectrode Array with PEDOT:PSS Coated 3D Micro-cones for Electromyographic Recording

J. Lu, M. Zia, M. J. Williams, A. L. Jacob, B. Chung, S. J. Sober, M. S. Bakir

This paper develops a flexible 3D microelectrode array with PEDOT:PSS coating for high-quality EMG recording, achieving high SNR and improved impedance.

bioRxiv · Feb 3, 2022 · PreprintBioengineering

Reduced Pathogenicity of the SARS-CoV-2 Omicron Variant in Hamsters

K. McMahan, V. Giffin, L. Tostanoski, B. Chung, M. Siamatu, M. Suthar, P. Halfmann, Y. Kawaoka, C. Piedra-Mora, A. Martinot, S. Kar, H. Andersen, M. G. Lewis, D. H. Barouch

This study shows the SARS-CoV-2 Omicron variant causes less weight loss in hamsters than previous variants, suggesting reduced lower respiratory tract disease severity.

bioRxiv · Jan 2, 2022Microbiology

G-quadruplex RNA motifs influence gene expression in the malaria parasite Plasmodium falciparum

F. Dumetz, E. Y.-C. Chow, L. M. Harris, M. I. Umar, A. Jensen, B. Chung, T. F. Chan, C. J. Merrick, C. K. Kwok

This study identifies RNA G-quadruplexes in Plasmodium falciparum and shows they influence translation of specific genes, including virulence factors.

bioRxiv · Mar 8, 2021Microbiology

Atg8a interacts with transcription factor Sequoia to control the expression of autophagy genes in Drosophila

A.-C. Jacomin, S. Petridi, M. DiMonaco, A. Jain, Z. Bhujabal, N. Mulakkal, A. Palara, E. Powell, B. Chung, C. Zampronio, A. Jones, A. Cameron, T. Johansen, I. Nezis

This study identifies Atg8a's interaction with Sequoia and other proteins to regulate autophagy gene expression in Drosophila.

bioRxiv · Apr 17, 2019 · PreprintCell Biology

Multi-ATOM: Ultrahigh-throughput single-cell quantitative phase imaging with subcellular resolution

K. Lee, A. Lau, A. Tang, M. Wnag, A. Mok, B. Chung, W. Yan, H. C. Shum, K. Cheah, G. Chan, H. So, K. Wong, K. Tsia

The paper introduces multi-ATOM, a high-throughput QPI method that enables subcellular resolution and accurate cell-type classification without compromising speed or quality.

bioRxiv · Jan 3, 2019Bioengineering