Author

O. Ponomarova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Amzallag· 1 shared A. Friedman· 1 shared A. J. M. Walhout· 1 shared A. Sahu· 1 shared A. Wagner· 1 shared B. Miao· 1 shared B. W. Fox· 1 shared C. Benes· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Amzallag

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2 papers

Recent·Most cited

BiochemistrybioRxivMay 16, 2022

A D-2-Hydroxyglutarate dehydrogenase mutant reveals a critical role for ketone body metabolism in Caenorhabditis elegans development

O. Ponomarova, H. Zhang, X. Li…·A. J. M. Walhout

This study shows that in C. elegans, D-2HG is produced via the propionate shunt and that loss of dhgd-1 causes embryonic lethality by disrupting ketone body metabolism, which can be rescued by vitamin B12 or 3-hydroxybutyrate.

DOI 10.1371/journal.pbio.3002057

C. elegansexperimental assay

Cancer BiologybioRxivApr 8, 2018

Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy

A. Sahu, J. Sang Lee, G. Zhang…·E. Ruppin

The paper predicts synthetic rescue mediators of resistance to targeted and immunotherapy using tumor transcriptomics and survival data from 10,000 TCGA patients, validating predictions through experimental screens.

DOI 10.15252/msb.20188323

humanbulk RNA-seq