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O. V. Povstyan

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Biophysics· 1

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Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

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A. C. Kalli· 1 shared A. J. Hyman· 1 shared D. De Vecchis· 1 shared D. J. Beech· 1 shared J. Chong· 1 shared J. Shi· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperBiophysics

A. C. Kalli

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1 paper

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BiophysicsBiophysical JournalPeer-reviewedApr 1, 2021

Computational reconstruction of the complete Piezo1 structure reveals a unique footprint and specific lipid interactions

J. Chong, D. De Vecchis, A. J. Hyman…·A. C. Kalli

This study computationally reconstructs the full-length Piezo1 structure, revealing its trilobed topology, lipid interactions, and how membrane stiffness affects its shape.

DOI 10.1016/j.bpj.2021.02.003

protein structuredeep learning

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