Non-canonical Wnt signalling initiates scarring in biliary disease
DH Wilson, RP Mellin, NT Younger, EJ Jarman, A Raven, P Chen, CH Dean, DJ Henderson, TJ Kendall, L Boulter
This study identifies non-canonical Wnt signalling as a driver of biliary scarring and shows that inhibiting Wnt ligands reduces fibrosis in cholestatic diseases.
bioRxiv · Mar 19, 2018 · PreprintPhysiology