Temperature Evolution Following Joint Loading Promotes Chondrogenesis by Synergistic Cues via Calcium Signaling
N. Nasrollahzadeh, P. Karami, J. Wang, L. Bagheri, Y. Guo, P. Abdel-Sayed, L. Laurent Applegate, D. P. Pioletti
This study shows that combined thermal and mechanical stimuli synergistically enhance chondrogenesis through calcium signaling via TRPV4 channels.
bioRxiv · Jun 29, 2021Bioengineering