P. Barraud

Structural basis for human mitochondrial tRNA maturation

This study reports cryo-EM structures of human mitochondrial tRNA maturation complexes, revealing the molecular mechanisms of tRNA processing steps and their sequential order.

A bacterial effector directly targets Arabidopsis Argonaute 1 to suppress Pattern-triggered immunity and cause disease

This study shows that the bacterial effector HopT1-1 targets Arabidopsis AGO1 to suppress miRNA function and PTI, leading to disease.

Different modification pathways for m1A58 incorporation in yeast elongator and initiator tRNAs

This study identifies distinct modification pathways for m1A58 incorporation in yeast elongator and initiator tRNAs, showing it is stimulated by different modifications in each context.

DNA methylation at a single cytosine embedded in the W-box cis-element repels binding of WRKY transcription factors through steric hindrance

The paper shows DNA methylation at a W-box cytosine repels WRKY TF binding through steric hindrance, using structural modeling and in vitro experiments.