W. Yue

This study reports cryo-EM structures of human mitochondrial tRNA maturation complexes, revealing the molecular mechanisms of tRNA processing steps and their sequential order.

This study identifies CDC5L as a transcriptional repressor that prevents spontaneous stress granule formation by suppressing PERK-eIF2 signaling.

This study maps ex vivo terminal erythropoiesis from umbilical cord blood mononuclear cells and pluripotent stem cells, identifying differences in regulatory dynamics and CD99 expression affecting erythroid expansion and maturation.

GliaTrap is a biodegradable non-swelling hydrogel with tuned release of a chemoattractant to attract invading glioma cells and serve as delivery platform for local therapeutics.

The paper identifies three deeply conserved super-enhancers in placental mammals that are essential for maintaining stem cell pluripotency.

The paper captures structural snapshots of actin and tubulin folding within the TRiC chaperonin using cryo-EM, revealing how substrates interact with the chamber during folding.

The paper shows that KDM3A and KDM3B, along with OCT4/SOX2, regulate H3K9 methylation to maintain pluripotency in porcine-induced pluripotent stem cells.

The paper maps the genome-wide association of capsid proteins with viral RNA in Dengue and Zika viruses, showing non-uniform binding patterns and sequence preferences.

This study presents the 2.5 Å resolution crystal structure of human MTHFR, revealing its architecture and how phosphorylation and SAM binding regulate its activity.

This study investigates how zinc(II) binding to ISCU affects Fe-S cluster biosynthesis and shows that Met140 variants of ISCU do not bypass FXN's role in the absence of FXN.