Author

P. Becker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:protein design· 1

Frequent Co-Authors

A. D. Cameron· 1 shared A. Ting· 1 shared A. Valentin-Torres· 1 shared C. Hull· 1 shared D. A. Boardman· 1 shared D. H. Brotherton· 1 shared D. Niopek· 1 shared E. Nova-Lamperti· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperBiochemistry

A. D. Cameron

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mechanism of substrate binding and transport in BASS transporters

P. Becker, F. B. Naughton, D. H. Brotherton, R. Pacheco-Gomez, O. Beckstein, A. D. Cameron

This study determines the crystal structure of a BASS transporter in complex with pantoate, revealing how substrate binding is coupled to sodium ion binding and transport through conformational changes.

bioRxiv · Jun 2, 2023Biochemistry

Dissecting the Determinants of Domain Insertion Tolerance and Allostery in Proteins

J. Mathony, S. Aschenbrenner, P. Becker, D. Niopek

The paper systematically assesses domain insertion permissibility in proteins and identifies sequence conservation as a key determinant, enabling the design of switchable protein hybrids.

bioRxiv · Apr 11, 2023Bioengineering

Augmented expansion of Treg cells from healthy and autoimmune subjects via adult progenitor cell co-culture.

J. L. Reading, V. Roobrouck, C. Hull, P. Becker, J. Beyens, A. Valentin-Torres, D. A. Boardman, E. Nova-Lamperti, S. Stubblefield, G. Lombardi, R. Deans, A. Ting, T. Tree

This study shows that co-culturing Treg cells with MAPC enhances their expansion, improves their functional properties, and increases their yield from autoimmune patients.

bioRxiv · Dec 3, 2020Immunology