Author

S. Aschenbrenner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

R. Eils· 2 shared A. Jauch· 1 shared B. Schoell· 1 shared C. Conrad· 1 shared C. Dietz· 1 shared C. Herrmann· 1 shared C. Klein· 1 shared C. Liesche· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

R. Eils

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dissecting the Determinants of Domain Insertion Tolerance and Allostery in Proteins

J. Mathony, S. Aschenbrenner, P. Becker, D. Niopek

The paper systematically assesses domain insertion permissibility in proteins and identifies sequence conservation as a key determinant, enabling the design of switchable protein hybrids.

bioRxiv · Apr 11, 2023Bioengineering

Induced aneuploidy disrupts MCF10A acini formation and CCND1 expression

M. Waschow, Q. Wang, P. Saary, C. Klein, S. Aschenbrenner, K. Jechow, L. Maier, S. Tirier, B. Schoell, I. Chudoba, C. Dietz, D. Dreidax, A. Jauch, M. Sprick, C. Herrmann, , C. Conrad

This study shows that induced aneuploidy disrupts MCF10A acini formation and upregulates CCND1 expression through altered promoter-enhancer interactions.

bioRxiv · Dec 15, 2019 · PreprintCancer Biology

CD95 receptor activation by ligand-induced trimerization is independent of its partial pre-ligand assembly

C. Liesche, J. Berndt, F. Fricke, S. Aschenbrenner, M. Heilemann, R. Eils, J. Beaudouin

This paper investigates how CD95 receptor activation occurs through ligand-induced trimerization, showing that receptor multimerization follows ligand binding while FADD recruitment is delayed, and that soluble CD95L is a poor inducer of apoptosis due to inefficient FADD recruitment.

bioRxiv · Apr 2, 2018 · PreprintCell Biology