Author

P. Brookes

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Biology Disciplines

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Biochemistry· 1

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

J. Munger· 1 shared J. Zhang· 1 shared K. Nehrke· 1 shared K. Welle· 1 shared S. Ghaemmaghami· 1 shared S. Nadtochiy· 1 shared X. Schafer· 1 shared Y. T. Wang· 1 shared

Activity by Year

2017-2017 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

J. Munger

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1 paper

Recent·Most cited

Potential Mechanisms Linking SIRT Activity And Hypoxic 2-Hydroxyglutarate Generation: No Role For Direct Enzyme (De)acetylation

S. Nadtochiy, Y. T. Wang, J. Zhang, K. Nehrke, X. Schafer, K. Welle, S. Ghaemmaghami, J. Munger, P. Brookes

This study investigates whether sirtuin-mediated acetylation regulates 2-HG production by metabolic enzymes, finding no direct link between enzyme acetylation and 2-HG generation.

bioRxiv · May 24, 2017Biochemistry