MicrobiologybioRxiv
A squalene-hopene cyclase in Schizosaccharomyces japonicus represents a eukaryotic adaptation to sterol-independent anaerobic growth
J. Bouwknegt, S. J. Wiersma, R. A. Ortiz-Merino…·J. T. Pronk
This study identifies a squalene-hopene cyclase in Schizosaccharomyces japonicus that enables sterol-independent anaerobic growth by synthesizing hopanoids as sterol surrogates.
DOI 10.1073/pnas.2105225118