Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson Syndrome and Toxic epidermal necrolysis.
A. Gibson, R. Ram, R. Gangula, Y. Li, E. Mukherjee, A. M. Palubinsky, C. N. Campbell, M. Thorne, K. C. Konvinse, P. Choshi, P. Deshpande, S. Pedretti, R. T. O'Neil, C. N. Wanjalla, S. A. Kalams, , E. J. Phillips
The paper uses multiomic single-cell sequencing to analyze SJS/TEN patients' skin and blister fluid, identifying tissue-specific immune responses and T-cell clonotypes involved in pathogenesis.
bioRxiv · Nov 26, 2023Immunology