Author

P. Doublet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

C. Andrea· 2 shared C. Michard· 2 shared S. Jarraud· 2 shared X. Charpentier· 2 shared A. Vianney· 1 shared C. Jaboulay· 1 shared E. Kay· 1 shared G. Descours· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersMicrobiology

C. Andrea

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dual control of host actin polymerization by a Legionella effector pair

M. Pillon, C. Michard, N. Baïlo, J. Bougnon, K. Picq, O. Dubois, C. Andrea, L. Attaiech, V. Daubin, S. Jarraud, E. Kay, P. Doublet

This study identifies LegK2 and VipA as antagonistic effectors in Legionella pneumophila that regulate actin polymerization and bacterial virulence through distinct substrates.

bioRxiv · May 15, 2023Microbiology

Deciphering Legionella effector delivery by Icm/Dot secretion system reveals a new role for c-diGMP signaling

J. Allombert, C. Jaboulay, C. Michard, C. Andrea, X. Charpentier, A. Vianney, P. Doublet

The paper investigates the dynamics of multi-effector secretion by the Legionella pneumophila Icm/Dot T4SS and identifies c-diGMP signaling as a regulator of effector translocation timing.

bioRxiv · Apr 22, 2021 · PreprintMicrobiology

KKL-35 Exhibits Potent Antibiotic Activity Against Legionella Species Independently Of Trans-Translation Inhibition

R. Brunel, G. Descours, I. Durieux, P. Doublet, S. Jarraud, X. Charpentier

This study shows KKL-35, an oxadiazole compound, effectively inhibits Legionella species growth without relying on trans-translation inhibition.

bioRxiv · Nov 15, 2017Microbiology