Author

P. Drane

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Detappe· 1 shared B. Bragantini· 1 shared D. Chowdhury· 1 shared D. J. Schuller· 1 shared G. Cui· 1 shared G. Mer· 1 shared J. R. Thompson· 1 shared L. I. James· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Detappe

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1 paper

Recent·Most cited

An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering

G. Cui, M. V. Botuyan, P. Drane, Q. Hu, B. Bragantini, J. R. Thompson, D. J. Schuller, A. Detappe, M. T. Perfetti, L. I. James, S. V. Frye, D. Chowdhury, G. Mer

This study identifies an autoinhibited state of 53BP1 stabilized by small molecule ligands, which shift its conformational equilibrium and inhibit chromatin recruitment.

bioRxiv · Apr 20, 2023Biochemistry