Author

G. Cui

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Ecology· 3 Plant Biology· 3 Cancer Biology· 2 Immunology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 10 Assay:bulk RNA-seq· 5 Research Focus:cell type annotation· 4 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:DNA methylation· 2

Frequent Co-Authors

J. Wang· 3 shared M. Aranda· 3 shared Y. Li· 3 shared C. R. Voolstra· 2 shared C. T. Michell· 2 shared J. Mi· 2 shared P. Li· 2 shared Q. Wang· 2 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersPlant Biology

J. Wang

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12 papers

Recent·Most cited

Establishment of hairy root culture and its genetic transformation of Stephania tetrandra S. Moore for production of BIAs

X. Zhang, J. Bu, Y. Zhao, Q. Li, X. Li, Y. Ma, J. Tang, J. Wang, C. Lai, G. Cui, J. Guo, L. Huang

This paper establishes a hairy root culture and genetic transformation system in Stephania tetrandra to enhance bisbenzylisoquinoline alkaloid production.

bioRxiv · May 17, 2023 · PreprintPlant Biology

An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering

G. Cui, M. V. Botuyan, P. Drane, Q. Hu, B. Bragantini, J. R. Thompson, D. J. Schuller, A. Detappe, M. T. Perfetti, L. I. James, S. V. Frye, D. Chowdhury, G. Mer

This study identifies an autoinhibited state of 53BP1 stabilized by small molecule ligands, which shift its conformational equilibrium and inhibit chromatin recruitment.

bioRxiv · Apr 20, 2023Biochemistry

Multi-omics and Pharmacological Characterization of Patient-derived Glioma Cell Lines

M. Wu, R. Yuan, N. Ji, T. Lu, T. Wang, J. Zhang, M. Li, P. Cao, J. Zhao, G. Li, J. Li, Y. Li, Y. Tang, Z. Gao, X. Wang, , J. Chen

This study characterizes 52 patient-derived glioma cell lines with whole-genome sequencing, RNA-seq, and drug response screening, identifying three subtypes and their drug sensitivities and tumorigenic potential.

bioRxiv · Feb 20, 2023 · PreprintCancer Biology

Liver type 1 innate lymphoid cells lacking IL-7 receptor are a native killer cell subset fostered by parenchymal niches

T. Asahi, S. Abe, G. Cui, A. Shimba, T. Nabekura, H. Miyachi, S. Kitano, K. Ohira, J. M. Dijkstra, M. Miyazaki, A. Shibuya, H. Ohno, K. Ikuta

The paper identifies a novel liver-specific ILC1 subset lacking IL-7 receptor that develops from fetal liver progenitors and exhibits constitutive cytotoxic activity.

bioRxiv · Nov 3, 2022Immunology

Nitrogen competition is the general mechanism underlying cnidarian-Symbiodiniaceae symbioses

G. Cui, J. Mi, A. Moret, H. Zhong, S.-H. Hung, S. Al-Babili, M. Aranda

The paper identifies nitrogen competition as the mechanism controlling cnidarian-Symbiodiniaceae symbioses, showing glucose limits symbiont nitrogen availability while ammonium promotes growth.

bioRxiv · Jun 30, 2022 · PreprintEcology

Characteristics of N6-methyladenosine modification during sexual reproduction of Chlamydomonas reinhardtii

Y. Lv, F. Han, M. Liu, T. Zhang, G. Cui, J. Wang, Y. Yang, Y. Yang, W. Yang

This study identifies m6A modification patterns and functions during sexual reproduction in Chlamydomonas reinhardtii, showing its role in regulating microtubule-based processes.

bioRxiv · Mar 26, 2022Plant Biology

Gastric cancer derived exosomes induce peritoneal mesothelial cell EMT through TGF-β1/Smads pathway to promote peritoneal metastasis

J. Dong, Z. Zhu, G. Cui, Z. Zhang, J. Yue, Y. Zhang, X. Yao, M. Huo, J. Wei, Q. Wang, L. Dai, P. Li, X.-P. Liu

This study shows GC-derived exosomes induce EMT in peritoneal mesothelial cells via TGF-β1/Smads pathway, enhancing GC cell migration and adhesion.

bioRxiv · Jul 23, 2021 · PreprintCancer Biology

Oxidized Lipids and CD36-Mediated Lipid Peroxidation in CD8 T Cells Suppress Anti-Tumor Immune Responses

S. Xu, O. Chaudhary, P. Rodriguez-Morales, X. Sun, R. Zappasodi, Z. Xu, A. F. M. Pinto, A. Williams, D. Chen, J. S. Low, Y. Farsakoglu, W. Tang, H. Wang, S. K. Varanasi, B. McDonald, , S. M. Kaech

This study identifies CD36-mediated lipid peroxidation driven by oxidized lipids as a mechanism suppressing anti-tumor CD8 T cell functions in murine tumors.

bioRxiv · Sep 3, 2020Immunology

Characterization of the gut DNA and RNA viromes in a cohort of Chinese residents and visiting Pakistanis

Q. Yan, Y. Wang, X. Chen, H. Jin, G. Wang, K. Guan, Y. Zhang, P. Zhang, T. Ayaz, Y. Liang, J. Wang, G. Cui, Y. Sun, M. Xiao, A. Zhang, , T. Ma

This study compares the gut DNA and RNA viromes of Chinese residents and Pakistani visitors, finding ethnic origin significantly influences virome composition and diversity.

bioRxiv · Jul 28, 2020Microbiology

Anchorene is an endogenous diapocarotenoid required for anchor root formation in Arabidopsis

K. Jia, A. J. Dickinson, J. Mi, G. Cui, N. M. Kharbatia, X. Guo, E. Sugiono, M. Aranda, M. Rueping, P. N. Benfey, S. Al-Babili

The paper identifies anchorene, a carotenoid-derived dialdehyde, as an endogenous signal required for anchor root formation in Arabidopsis, showing it modulates auxin homeostasis.

bioRxiv · Dec 14, 2018 · PreprintPlant Biology

DNA methylation regulates transcriptional homeostasis of algal endosymbiosis in the coral model Aiptasia

Y. Li, Y. J. Liew, G. Cui, M. J. Cziesielski, N. Zahran, C. T. Michell, C. R. Voolstra, M. Aranda Lastra

The paper investigates DNA methylation's role in maintaining transcriptional homeostasis during algal endosymbiosis in Aiptasia, finding it reduces transcriptional noise and regulates symbiosis-related processes.

bioRxiv · Jan 24, 2018Ecology

Epigenome-associated phenotypic acclimatization to ocean acidification in a reef-building coral

Y. J. Liew, D. Zoccola, Y. Li, E. Tambutte, A. A. Venn, C. T. Michell, G. Cui, E. S. Deutekom, J. A. Kaandorp, C. R. Voolstra, S. Foret, D. Allemand, S. Tambutte, M. Aranda

This study shows DNA methylation in corals reduces transcriptional noise and enables phenotypic acclimatization to ocean acidification by altering cell and polyp sizes.

bioRxiv · Sep 13, 2017Ecology