MicrobiologybioRxivPreprint
Activation of the Cpx-envelope stress response system promotes tolerance to antibacterials delivered by arginine-rich peptides and aminoglycosides in Escherichia coli
J. Frimodt-Moller, A. Koulouktsis, G. Charbon…·A. Lobner-Olesen
The paper shows that Escherichia coli resistance to arginine-rich CPP-PNA conjugates involves the constitutively active Cpx-envelope stress response system, which reduces membrane potential and increases tolerance to aminoglycosides.
DOI 10.1101/2020.08.31.274910