Fast fluorescence lifetime imaging reveals the aggregation processes of α-synuclein and polyglutamine in aging Caenorhabditis elegans
R. F. Laine, T. Sinnige, K. Y. Ma, A. J. Haack, C. Poudel, P. Gaida, N. Curry, M. Perni, E. A. A. Nollen, C. M. Dobson, M. Vendruscolo, G. S. Kaminski Schierle, C. F. Kaminski
This study uses fast TG-FLIM to analyze α-synuclein and polyglutamine aggregation in aging C. elegans, revealing differences in their aggregation kinetics and amyloid-like features.
bioRxiv · Nov 16, 2018Biophysics