The human placenta shapes the phenotype of decidual macrophages.
S. Vondra, A.-L. Hoebler, A. I. Lackner, J. Raffetseder, Z. N. Mihalic, A. Vogel, L. Saleh, V. Kunihs, P. Haslinger, M. Wahrmann, H. Husslein, R. Oberle, J. Kargl, S. Haider, P. Latos, , J. Pollheimer
This study identifies distinct macrophage phenotypes in human decidua basalis and parietalis, showing that placenta-derived trophoblasts induce a pregnancy-tolerant macrophage phenotype.
bioRxiv · Mar 29, 2022Immunology