Systems BiologyNature CommunicationsPeer-reviewed
Sequestration of histidine kinases by non-cognate response regulators establishes a threshold level of stimulation for bacterial two-component signaling
Gaurav D. Sankhe, Rubesh Raja, Devendra Pratap Singh…·Deepak Kumar Saini
The paper shows that non-cognate response regulators sequester phosphorylated histidine kinases, establishing a threshold for bacterial two-component signaling to prevent over-response to weak signals.
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