Author

P. J. Lund

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:biophysical modeling· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

B. A. Garcia· 2 shared A. Bajic· 1 shared A. Q. Rashoff· 1 shared C. D. Allis· 1 shared C. Petucci· 1 shared E. S. Friedman· 1 shared G. D. Wu· 1 shared K. L. Diehl· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

B. A. Garcia

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Author profile →

2 papers

Recent·Most cited

Stable Isotope Tracing In Vivo Reveals A Metabolic Bridge Linking The Microbiota To Host Histone Acetylation

P. J. Lund, L. A. Gates, M. Leboeuf, S. A. Smith, L. Chau, E. S. Friedman, M. Lopes, Y. Saiman, M. S. Kim, C. Petucci, C. D. Allis, G. D. Wu, B. A. Garcia

This study uses stable isotope tracing to show that gut microbiota supply carbon for host histone acetylation, linking microbial metabolism to host epigenetic regulation.

bioRxiv · Jul 5, 2021Biochemistry

PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism

S. U. Jain, T. J. Do, P. J. Lund, A. Q. Rashoff, M. Cieslik, K. L. Diehl, A. Bajic, N. Juretic, S. Deshmukh, S. Venneti, T. W. Muir, B. A. Garcia, N. Jabado, P. W. Lewis

This study identifies EZHIP as a PRC2 inhibitor in PFA ependymomas that mimics the H3 K27M oncohistone by disrupting PRC2 activity and H3K27me3 levels.

Nature Communications · May 13, 2019Peer-reviewedCancer Biology