P. J. Steinbach

Evidence for intrinsic DNA dynamics and deformability in damage sensing by the Rad4/XPC nucleotide excision repair complex

The paper investigates DNA dynamics and deformability in Rad4/XPC damage sensing using T-jump and FRET techniques, showing rapid fluctuations and unwound/bent conformations at lesion sites.

Static kinks or flexible hinges: conformational distributions of bent DNA bound to integration host factor mapped by fluorescence lifetime measurements

This study uses fluorescence lifetime measurements to show that IHF-DNA complexes exhibit conformational flexibility, with some DNA remaining unbent or partially bent despite IHF-induced kinking.