Antibiotic collateral sensitivity is contingent on the repeatability of evolution
D. Nichol, J. Rutter, C. Bryant, A. M. Hujer, S. Lek, M. D. Adams, P. Jeavons, A. Anderson, R. Bonomo, J. Scott
This study shows that sequential antibiotic treatments may overestimate therapeutic benefits due to stochastic resistance or susceptibility outcomes in E. coli.
bioRxiv · Jan 9, 2019Evolutionary Biology