Author

P. Johe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

C. Kersten· 1 shared E. Jaenicke· 1 shared H. Neuweiler· 1 shared T. Schirmeister· 1 shared U. A. Hellmich· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

C. Kersten

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1 paper

Recent·Most cited

Structure, interdomain dynamics and pH-dependent autoactivation of pro-rhodesain, the main lysosomal cysteine protease from African trypanosomes

P. Johe, E. Jaenicke, H. Neuweiler, T. Schirmeister, C. Kersten, U. A. Hellmich

This study determines the crystal structure of pro-rhodesain, identifies interdomain dynamics, and reveals a pH-dependent autoactivation mechanism in trypanosomal cathepsin L-like proteases.

bioRxiv · Nov 10, 2020Biochemistry