Molecular basis of VEGFR1 autoinhibition at the plasma membrane
M. P. Chakraborty, D. Das, P. Mondal, P. Kaul, S. Bhattacharyya, P. K. Das, R. Das
This study identifies a mechanism by which VEGFR1 remains constitutively inactive through juxtamembrane inhibition and phosphatase activity, explaining its differential regulation compared to VEGFR2.
bioRxiv · Jun 8, 2023Biochemistry